翻訳と辞書 Words near each other ・ Long'an County ・ Long'an District ・ Long's Bar, California ・ Long's Regiment ・ Long, Broad and Sharpsight ・ Long, Lamoreaux & Long ・ Long, Long Ago ・ Long, Long Way from Home ・ Long, Long Way to Go ・ Long, Long, Long ・ Long, McCorkle and Murray Houses ・ Long, Oklahoma ・ Long, Slow Kisses ・ Long, Somme ・ Long-A-Coming Depot ・ Long-acting beta-adrenoceptor agonist ・ Long-acting reversible contraception ・ Long-armed squid ・ Long-beaked common dolphin ・ Long-beaked echidna ・ Long-bearded axe ・ Long-bearded melidectes ・ Long-Bell Lumber Company ・ Long-billed bernieria ・ Long-billed bush warbler ・ Long-billed corella ・ Long-billed crombec ・ Long-billed crow ・ Long-billed cuckoo ・ Long-billed curlew Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Long-acting beta-adrenoceptor agonist ： ウィキペディア英語版 Long-acting beta-adrenoceptor agonist Long-acting beta-adrenoceptor agonists (LABAs, more specifically β2-agonists) are usually prescribed for moderate to severe persistent asthma patients or patients with chronic obstructive pulmonary disease (COPD). They are designed to reduce the need for shorter-acting β2-agonists such as salbutamol, as they have a duration of action of approximately 12 hours in comparison with the 4- to 6-hour duration of salbutamol, making them candidates for sparing high doses of corticosteroids or treating nocturnal asthma and providing symptomatic improvement in patients with COPD. With the exception of formoterol, long-acting β2-agonists are not recommended for the treatment of acute asthma exacerbations because of their slower onset of action compared to salbutamol. Their long duration of action is due to the addition of a long, lipophilic side-chain that binds to an exosite on adrenergic receptors. This allows the active portion of the molecule to continuously bind and unbind at β2 receptors in the smooth muscle in the lungs. ==Medical uses== When combined with inhaled steroids, beta-adrenoceptor agonists can improve symptoms. In children this benefit is uncertain and they may be potentially harmful.〔 They should not be used without an accompanying steroid due to an increased risk of severe symptoms, including exacerbation in both children and adults. At least with formoterol, an increased risk appears to be present even when steroids are used and this risk has not been ruled out for salmeterol. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Long-acting beta-adrenoceptor agonist」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.